Monkey Island!!!!!

Although... without a doubt, possibly the funniest game in the world is ZeroWing.. well.. the intro, and thats about it .
:idea: So what we've got to do is translate all the ingame text to Japanese and back again, and hey presto, a badly translated game which will take the world by storm!*

I could just be pessimistic and say that many publishers go the path of "we can't market a funny/immersive game storyline", so they must have fancy graphics.

*Not 100% guaranteed.