If your units are actually tiles (or something alike) then you need to take the tile coordinates and multiply them with the tileheight and -width. Then substract this value from the scrolling offset and you're set.

For example,
Your tiles are 32x32
The target tile = at 142,227
your scrolloffset = 4112, 6930

32*142= 4544
32*227= 7264

4544 - 4112 = 432
7264 - 6930 = 334


If this is not correct then show us of code, it might explain better what you have and how to deal with it.